Kubo Yoshiyuki

写真a

Title

Associate Professor

Laboratory Address

2630 Sugitani, Toyama City, Toyama, Japan

Research Fields, Keywords

Molecular Biopharmaceutics; Membrane Transporter; Blood-Retinal Barrier

Graduate School 【 display / non-display

  •  
    -
    2003.03

    Osaka University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Completed

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    -
    2000.03

    Osaka University  Graduate School, Division of Pharmaceutical Sciences  Master's Course  Completed

Degree 【 display / non-display

  • 2003.03 -  Ph.D.  Osaka University

Campus Career 【 display / non-display

  • 2013.07
     
     

    University of ToyamaGraduate School of Medicine and Pharmaceutical Sciences for Research   Advanced Biomedicine   Genome Pharmaceutical Science   Associate Professor  

  • 2013.07
     
     

    University of ToyamaFaculty of Pharmacy and Pharmaceutical Sciences   Department of Pharmacy   Associate Professor  

External Career 【 display / non-display

  • 2010.04
    -
    2011.03

    Tohoku University   Graduate School of Medicine   Assistant Professor  

  • 2008.04
    -
    2010.03

    Medical College of Georgia   Researcher  

  • 2006.04
    -
    2008.03

    Kanazawa University   Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology   Assistant Professor  

  • 2004.07
    -
    2006.03

    Kanazawa University   Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology   Research Assistant  

  • 2004.04
    -
    2004.06

    Kanazawa University   Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology  

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Academic Society Affiliations 【 display / non-display

  • 2004.04
     
     
     

    JSSX

Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Medical pharmacy

  • Functional biochemistry

  • Biological pharmacy

Qualification acquired 【 display / non-display

  • Pharmacist

 

Research project summary 【 display / non-display

  • We study the transport system of cationic compounds, including drugs and nutrients, at the blood-tissue barrier.

Papers 【 display / non-display

  • Investigation of receptor-mediated cyanocobalamin (vitamin B12) transport across the inner blood-retinal barrier using fluorescence-labeled cyanocobalamin

    Kinoshita Y, Nogami K, Jomura R, Akanuma S, Abe H, Inouye M, Kubo Y, Hosoya K

    Mol Pharm   15 ( 6 ) 3583 - 3594   2018.08

    Joint Work

  • Role of l-Type Amino Acid Transporter 1 at the Inner Blood-Retinal Barrier in the Blood-to-Retina Transport of Gabapentin.

    Akanuma SI, Yamakoshi A, Sugouchi T, Kubo Y, Hartz AMS, Bauer B, Hosoya KI

    Molecular pharmaceutics ( American Chemical Society ({ACS}) )  15 ( 6 ) 2327 - 2337   2018.06

    Joint Work

    DOI PubMed

  • Blood-to-Retina Transport of Fluorescence-Labeled Verapamil at the Blood-Retinal Barrier.

    Kubo Y, Nakazawa A, Akanuma SI, Hosoya KI

    Pharmaceutical research   35 ( 5 ) 93   2018.03

    Joint Work

    DOI PubMed

  • Expression and function of connexin 43 protein in mouse and human retinal pigment epithelial cells as hemichannels and gap junction proteins.

    Akanuma SI, Higashi H, Maruyama S, Murakami K, Tachikawa M, Kubo Y, Hosoya KI

    Experimental eye research   168   128 - 137   2018.03

    Joint Work

    DOI PubMed

  • Role of cationic drug-sensitive transport systems at the blood-cerebrospinal fluid barrier in para-tyramine elimination from rat brain.

    Akanuma SI, Yamazaki Y, Kubo Y, Hosoya KI

    Fluids and barriers of the CNS   15 ( 1 ) 1   2018.01

    Joint Work

    DOI PubMed

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Books 【 display / non-display

  • Experimental Approaches to Study Drug Transporters. ‘You G / Morris, ME / Drug Transporters 2nd edition

    Kubo Y, Kato Y, Tsuji A (Part: Joint Work )

    Wiley  2014.08

  • Vitamin transport across the blood-retinal barrier: focus on vitamins C, E and biotin. ‘Preedy, VR / Handbook of Diet, Nutrition and the Eye 1st edition

    Ken-ichi Hosoya and Yoshiyuki Kubo (Part: Joint Work )

    Academic Press/ELSEVIER  2014.04

  • ‘Inner Blood-Retinal Barrier Transporters: Relevance to Diabetic Retinopathy’. Ola, Mohammad S / "Diabetic Retinopathy", open access publication (http://www.intechopen.com/books/diabetic-retinopathy)

    Kubo Y, Hosoya K (Part: Joint Work )

    Intech  2012.05

  • Experimental Approaches to Study Drug Transporters. [You, Guofeng / Morris, Marilyn E "Drug Transporters]

    Kubo Y, Kato Y, Tsuji A (Part: Joint Work )

    Wiley  2007.01

  • In vivo analysis to study transport across the blood-retinal barrier

    Kubo Y, Akanuma S, Hosoya K (Part: Single Work )

    Humana Press  2018.12

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Review Papers 【 display / non-display

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Academic Awards Received 【 display / non-display

  • JSSX Award for Young Scientists

    2016.10.14    

Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for Young Scientists (Start-up)

    Project Year: 2011.04  -  2013.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2017.04  -   

  • Grant-in-Aid for challenging Exploratory Research

    Project Year: 2016.04  -  2018.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2014.04  -  2017.03 

  • Grant-in-Aid for Exploratory Research

    Project Year: 2012.04  -  2014.03 

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Presentations 【 display / non-display

  • Impact of carrier-mediated transport of cationic neuroprotectants to the retina

    The First International Symposium on Toyama-Asia-Africa Pharmaceutical Network  2016  -  2016 

  • 10th international conferance on cerebral vascular biology  2013.06  -  2013.06 

  • 10th international conferance on cerebral vascular biology  2013.06  -  2013.06 

 

Academic Activity 【 display / non-display

  • 2017.04
    -
    2018.03

    JSSX  

Social Contribution 【 display / non-display

  • Editorial Board Member, Journal of Pharmaceutical Sciences

    2017.01
     
     

  • Editorial Board Member, Drug Metabolism and Pharmacokinetics

    2017.01