ISOBE Masaharu

写真a

Title

Professor

Research Fields, Keywords

Molecular Genetics

Campus Career 【 display / non-display

  • 2019.10
     
     

    University of ToyamaAcademic Assembly   Faculty of Engineering   Professor  

  • 2019.10
     
     

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2018.04
    -
    2019.09

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2006.04
    -
    2019.09

    University of ToyamaGraduate School of Science and Engineering for Research   Life, Information and System Sciences   Human and Life Information Systems   Professor  

  • 2005.10
    -
    2018.03

    University of ToyamaFaculty of Engineering   Department of Life Sciences and Bioengineering   Professor  

Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Human genetics

  • Molecular Oncology

  • Genome Medical Science

  • General medical chemistry

 

Papers 【 display / non-display

  • A candidate gene of Alzheimer diseases was mutated in senescence-accelerated mouse prone (SAMP) 8 mice.

    Akbor MM, Kim J, Nomura M, Sugioka J, Kurosawa N, Isobe M

    Biochemical and biophysical research communications   572   112 - 117   2021.08

    Joint Work

    DOI PubMed

  • Polymorphic SERPINA3-R124C reduces pathogenesis of its wild type by shortening the lifetime of oligomeric Aβ.

    Akbor MM, Kurosawa N, Tanaka M, Isobe M

    Bioscience, biotechnology, and biochemistry   85 ( 8 ) 1861 - 1868   2021.07

    Joint Work

    DOI PubMed

  • Polymorphic SERPINA3 prolongs oligomeric state of amyloid beta.

    Akbor MM, Kurosawa N, Nakayama H, Nakatani A, Tomobe K, Chiba Y, Ueno M, Tanaka M, Nomura Y, Isobe M

    PloS one   16 ( 3 ) e0248027   2021

    Joint Work

    DOI PubMed

  • Development of a T-cell receptor mimic antibody targeting a novel Wilms tumor 1-derived peptide and analysis of its specificity.

    Kurosawa N, Midorikawa A, Ida K, Fudaba YW, Isobe M

    Cancer science   111 ( 10 ) 3516 - 3526   2020.08

    Joint Work

    DOI PubMed

  • High throughput development of TCR-mimic antibody that targets survivin-2B<sub>80-88</sub>/HLA-A*A24 and its application in a bispecific T-cell engager.

    Kurosawa N, Wakata Y, Ida K, Midorikawa A, Isobe M

    Scientific reports   9 ( 1 ) 9827   2019.07

    Joint Work

    DOI PubMed

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Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for challenging Exploratory Research

    Project Year: 2015.04  -  2017.03 

  • Grant-in-Aid for Exploratory Research

    Project Year: 2013.04  -  2015.03 

  • Grant-in-Aid for Exploratory Research

    Project Year: 2011.04  -  2013.03