ISOBE Masaharu

写真a

Research Fields, Keywords

Molecular Genetics

Campus Career 【 display / non-display

  • 2019.10
    -
    2022.03

    University of ToyamaAcademic Assembly   Faculty of Engineering   Professor  

  • 2019.10
    -
    2022.03

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2018.04
    -
    2019.09

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2006.04
    -
    2019.09

    University of ToyamaGraduate School of Science and Engineering for Research   Life, Information and System Sciences   Human and Life Information Systems   Professor  

  • 2005.10
    -
    2018.03

    University of ToyamaFaculty of Engineering   Department of Life Sciences and Bioengineering   Professor  

Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Human genetics

  • Molecular Oncology

  • Genome Medical Science

  • General medical chemistry

 

Papers 【 display / non-display

  • Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants.

    Ozawa T, Tani H, Anraku Y, Kita S, Igarashi E, Saga Y, Inasaki N, Kawasuji H, Yamada H, Sasaki SI, Somekawa M, Sasaki J, Hayakawa Y, Yamamoto Y, Morinaga Y, Kurosawa N, Isobe M, Fukuhara H, Maenaka K, Hashiguchi T, Kishi H, Kitajima I, Saito S, Niimi H

    mAbs   14 ( 1 ) 2072455   2022.01

    Joint Work

    DOI PubMed

  • A candidate gene of Alzheimer diseases was mutated in senescence-accelerated mouse prone (SAMP) 8 mice.

    Akbor MM, Kim J, Nomura M, Sugioka J, Kurosawa N, Isobe M

    Biochemical and biophysical research communications   572   112 - 117   2021.08

    Joint Work

    DOI PubMed

  • Polymorphic SERPINA3-R124C reduces pathogenesis of its wild type by shortening the lifetime of oligomeric Aβ.

    Akbor MM, Kurosawa N, Tanaka M, Isobe M

    Bioscience, biotechnology, and biochemistry   85 ( 8 ) 1861 - 1868   2021.07

    Joint Work

    DOI PubMed

  • Polymorphic SERPINA3 prolongs oligomeric state of amyloid beta.

    Akbor MM, Kurosawa N, Nakayama H, Nakatani A, Tomobe K, Chiba Y, Ueno M, Tanaka M, Nomura Y, Isobe M

    PloS one   16 ( 3 ) e0248027   2021

    Joint Work

    DOI PubMed

  • Development of a T-cell receptor mimic antibody targeting a novel Wilms tumor 1-derived peptide and analysis of its specificity.

    Kurosawa N, Midorikawa A, Ida K, Fudaba YW, Isobe M

    Cancer science   111 ( 10 ) 3516 - 3526   2020.08

    Joint Work

    DOI PubMed

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Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for challenging Exploratory Research

    Project Year: 2015.04  -  2017.03 

  • Grant-in-Aid for Exploratory Research

    Project Year: 2013.04  -  2015.03 

  • Grant-in-Aid for Exploratory Research

    Project Year: 2011.04  -  2013.03