TOHDA Michihisa



Associate Professor

Date of Birth


Laboratory Address

Section of Neuromedical Science, Division of Bioscience, Department of Research and Development, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194, Japan

Research Fields, Keywords

Wakan-yaku Universe, Serotonin 2C receptor (5HT2CR) , BNIP-3, RNA editing, Hochuekkito, Functional Mental Disdorer (FMD)

Laboratory Phone number


Laboratory Fax number


Homepage URL

Graduate School 【 display / non-display


    Hokkaido University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Unfinished Course

Campus Career 【 display / non-display

  • 2005.10

    University of ToyamaInstitute of Natural Medicine   Associate Professor  

Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Biological pharmacy

  • General internal medicine (including psychosomatic medicine)


Papers 【 display / non-display

  • Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease

    Thiratmatrakul S, Yenjai C, Waiwut P, Vajragupta O, Reubroycharoen P, Tohda M, and Boonyarat C.

    European Journal of Medicinal Chemistry   75   21 - 30   2014.01

    Joint Work

  • Evidence of Antidepressive Effects of a Wakan-yaku, Hochuekkito, in Depression Model Mice with Learned-Helplessness Behavior

    Tohda M. and Mingmalairak S.

    Evidence-Based Complementary and Alternative Medicine     2013.12

    Joint Work


  • Clarification of generating mechanisms of various types of depression based on the Wakan-yaku theory for development of novel depressants

    Tohda M.

    J. Trd. Med.   29   85 - 87   2012.04

    Single Work

  • γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression

    Sukma M, Tohda M, Suksamran S, Tantisira B.

    J Ethnopharmacol   135   450 - 454   2011.04

    Joint Work

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Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for Scientific Research(A)

    Project Year: 2009.04  -  2014.03