TOYOOKA Naoki

写真a

Title

Professor

Date of Birth

1961.01
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Graduating School 【 display / non-display 】

  • 　
    -
    1984.03

    Kinki University   Faculty of Pharmaceutical Science   Graduated

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Graduate School 【 display / non-display 】

  • 　
    -
    1989.03

    Kinki University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Completed

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Campus Career 【 display / non-display 】

  • 2018.04
    　
    　

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2017.04
    -
    2019.03

    University of ToyamaGraduate School of Innovative Life Science   Manager(Dean)  

  • 2010.04
    　
    　

    University of ToyamaGraduate School of Science and Engineering for Research   Nano and Functional Material Sciences   Functional Molecule Production Systems   Professor  

  • 2010.04
    -
    2018.03

    University of ToyamaFaculty of Engineering   Department of Life Sciences and Bioengineering   Professor  

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Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display 】

  • Organic chemistry

  • Medical pharmacy

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Qualification acquired 【 display / non-display 】

  • Pharmacist

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Research project summary 【 display / non-display 】

  • Drug discovery based upon organic synthesis

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Papers 【 display / non-display 】

  • Formal Synthesis of Gephyrotoxin 287C

    Takashima, K.; Toyooka, N.*

    Heterocycles, 2019, 99, 649-660.     2019

    Joint Work

  • Critical role of Cav3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice

    Tomita, S.; Sekiguchi, F.; Deguchi, T.; Miyazaki, T.; Ikeda, Y.; Tsubota, M.; Yoshida, S.; Nguyen, H. D.; Okada, T.; Toyooka, N. Kawabata, A.*

    Toxicology, 2019, 413, 33-39.     2019

    Joint Work

  • The novel small-molecule antagonist of PAC1 receptor attenuates formalin-induced inflammatory pain behaviors in mice

    Takasaki, I.*; Nakamura, K.; Shimodaira, A.; Watanabe, A.; Nguyen, H. D.; Okada, T.; Toyooka, N.; Miyata, A.; Kurihara, T.

    J. Pharmacol. Sci. 2019, 139, 129-132.     2019

    Joint Work

  • AS1949490, an inhibitor of 5'-lipid phosphatase SHIP2, promotes protein kinase C-dependent stabilization of brain-derived neurotrophic factor mRNA in cultured cortical neurons

    Tsuneki, H.; Yoshida, H.; Okamoto, K.; Yamaguchi, M.; Endo, K.; Nakano, A.; Tsuda, M.; Toyooka, N.; Wada, T.; Sasaoka, T.*

    Eur. J. Pharmacol. 2019, 851, 69-79.     2019

    Joint Work

  • Synthesis and odor properties of Phantolide analogues in racemic and optically active forms

    Kawasaki, M.*; Kuroyanagi, S.; Ito, T.; Morita, H.; Tanaka, Y.; Toyooka, N.

    Flavour Fragr. J. 2019, 34, 113-123.     2019

    Joint Work

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Books 【 display / non-display 】

  • Asymmetric Synthesis of Six-Membered Ring Heterocycles

    Toyooka, N. (Part： Single Work )

    John Wiley & Sons, Ltd.  2009

  • Enantioselective Synthesis of Substituted Pyrrolidine and Piperidines for Natural Product Synthesis

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    Research Signpost  2005

  • Synthetic Studies on Biologically Active Alkaloids Starting from Lactam-Type Chiral Building Blocks

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    Elsevier  2003

  • Synthetic Studies on Dart-Poison Frog Alkaloids

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    TRANSWORLD RESEARCH NETWORK  2002

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Review Papers 【 display / non-display 】

  • Synthesis of Poison-frog Alkaloids and Their Pharmacological Effects at Neuronal Nicotinic Acetylcholine Receptors

    Toyooka, N.*; Tsuneki, H.; Kobayashi, S.; Dejun, Z.; Kawasaki, M.; Kimura, I.; Sasaoka, T.; Nemoto, H.

    Current Chemical Biology ( AAA )  1   97 - 114   2007

    Introduction and explanation (scientific journal)   Joint Work

  • Application of Chiral Building Blocks for the Synthesis of Drugs

    Toyooka, N.*; Nemoto, H.

    Drugs Future ( AAA )  27   143 - 158   2002

    Introduction and explanation (scientific journal)   Joint Work

  • Synthetic Studies on Biologically Active Alkaloids

    Toyooka, N.*; Nemoto, H.

    Trends in Heterocyclic Chemistry ( AAA )  8   145 - 154   2002

    Introduction and explanation (scientific journal)   Joint Work

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Industrial Property 【 display / non-display 】

  • Preparation of fused tricyclic compounds as aldose reductase inhibitors

    Industrial Property No WO2009/078423 

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Grant-in-Aid for Scientific Research 【 display / non-display 】

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2015.04  -  2018.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year： 2013.04  -  2016.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2012.04  -  2015.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year： 2011.04  -  2014.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2010.04  -  2013.03 

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