TOYOOKA Naoki

写真a

Title

Professor

Date of Birth

1961.01

Graduating School 【 display / non-display

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    -
    1984.03

    Kinki University   Faculty of Pharmaceutical Science   Graduated

Graduate School 【 display / non-display

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    -
    1989.03

    Kinki University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Completed

Campus Career 【 display / non-display

  • 2019.10
     
     

    University of ToyamaAcademic Assembly   Faculty of Engineering   Professor  

  • 2019.10
     
     

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2018.04
    -
    2019.09

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2017.04
    -
    2019.03

    University of ToyamaGraduate School of Innovative Life Science   Manager(Dean)  

  • 2010.04
    -
    2019.09

    University of ToyamaGraduate School of Science and Engineering for Research   Nano and Functional Material Sciences   Functional Molecule Production Systems   Professor  

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Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Organic chemistry

  • Medical pharmacy

Qualification acquired 【 display / non-display

  • Pharmacist

 

Research project summary 【 display / non-display

  • Drug discovery based upon organic synthesis

Papers 【 display / non-display

  • Divergent Syntheses of Pumiliotoxin-Type Poison-Frog Alkaloids

    Okada, T.*; Ozaki, T.; Yamamoto, T.; Kasahara, H.; Kawasaki, M.; Toyooka, N.*

    Chem. Select 2021, 6, 1939-1945.     2021

    Joint Work

  • Anti-Austerity Activity of Thai Medical Plants: Chemical Constituents and Ant—Pancreatic Cancer Activities of Kaempferia parviflora

    Sun, S.; Kim. M. J.; Dibwe, D. F.; Omar, A. M.; Athikomkulchi, S.; Phrutivorapongkul, A.; Okada, T.; Tsuge, K.; Toyooka, N.; Awale, S.*

    Plants 2021, 10.     2021

    Joint Work

  • Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia

    Kikuya, M.; Furuichi, K.; Hirao, T.; Endo, S.; Toyooka, N.; Ito, K.; Aoki, S.*

    J. Pharmacol. Sci. 2021, 147, 1-8.     2021

    Joint Work

  • Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis

    Kitakami, R.; Inui, K.; Nakagawa, Y.; Sawai, Y.; Katayama, W.; Yokoyama, T.; Okada, T.; Kanamitsu, K.; Shinsaku Nakagawa, S.; Toyooka, N.; Mizuguchi, M.*

    Bioorg. Med. Chem. 2021, 44, 116292.     2021

    Joint Work

  • Total Synthesis of Decahydroquinoline Poison Frog Alkaloids ent-cis-195A and cis-211A

    Okada, T.*; Wu, N.; Takashima, K.; Ishimura, J.; Morita, H.; Ito, T.; Kodama, T.; Yamasaki, Y.; Akanuma, S.; Kubo, Y.; Hosoya, K.; Tsuneki, H.; Wada, T.; Sasaoka, T.; Shimizu, T.; Sakai, H.; Dwoskin, L. P.; Hussaini, S. R.; Saporito, R. A.; Toyooka, N.*

    Molecules 2021, 26, 7529.     2021

    Joint Work

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Books 【 display / non-display

  • Asymmetric Synthesis of Six-Membered Ring Heterocycles

    Toyooka, N. (Part: Single Work )

    John Wiley & Sons, Ltd.  2009

  • Enantioselective Synthesis of Substituted Pyrrolidine and Piperidines for Natural Product Synthesis

    Toyooka, N.*; Nemoto, H. (Part: Joint Work )

    Research Signpost  2005

  • Synthetic Studies on Biologically Active Alkaloids Starting from Lactam-Type Chiral Building Blocks

    Toyooka, N.*; Nemoto, H. (Part: Joint Work )

    Elsevier  2003

  • Synthetic Studies on Dart-Poison Frog Alkaloids

    Toyooka, N.*; Nemoto, H. (Part: Joint Work )

    TRANSWORLD RESEARCH NETWORK  2002

Review Papers 【 display / non-display

  • Synthesis of Poison-frog Alkaloids and Their Pharmacological Effects at Neuronal Nicotinic Acetylcholine Receptors

    Toyooka, N.*; Tsuneki, H.; Kobayashi, S.; Dejun, Z.; Kawasaki, M.; Kimura, I.; Sasaoka, T.; Nemoto, H.

    Current Chemical Biology ( AAA )  1   97 - 114   2007

    Introduction and explanation (scientific journal)   Joint Work

  • Application of Chiral Building Blocks for the Synthesis of Drugs

    Toyooka, N.*; Nemoto, H.

    Drugs Future ( AAA )  27   143 - 158   2002

    Introduction and explanation (scientific journal)   Joint Work

  • Synthetic Studies on Biologically Active Alkaloids

    Toyooka, N.*; Nemoto, H.

    Trends in Heterocyclic Chemistry ( AAA )  8   145 - 154   2002

    Introduction and explanation (scientific journal)   Joint Work

Industrial Property 【 display / non-display

  • Preparation of fused tricyclic compounds as aldose reductase inhibitors

    Industrial Property No WO2009/078423 

Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2015.04  -  2018.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2013.04  -  2016.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2012.04  -  2015.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2011.04  -  2014.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2010.04  -  2013.03 

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