TOYOOKA Naoki

写真a

Title

Professor

Date of Birth

1961.01
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Graduating School 【 display / non-display 】

  • 　
    -
    1984.03

    Kinki University   Faculty of Pharmaceutical Science   Graduated

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Graduate School 【 display / non-display 】

  • 　
    -
    1989.03

    Kinki University  Graduate School, Division of Pharmaceutical Sciences  Doctor's Course  Completed

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Campus Career 【 display / non-display 】

  • 2019.10
    　
    　

    University of ToyamaAcademic Assembly   Faculty of Engineering   Professor  

  • 2019.10
    　
    　

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2018.04
    -
    2019.09

    University of ToyamaFaculty of Engineering   Department of Engineering   Professor  

  • 2017.04
    -
    2019.03

    University of ToyamaGraduate School of Innovative Life Science   Manager(Dean)  

  • 2010.04
    -
    2019.09

    University of ToyamaGraduate School of Science and Engineering for Research   Nano and Functional Material Sciences   Functional Molecule Production Systems   Professor  

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Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display 】

  • Organic chemistry

  • Medical pharmacy

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Qualification acquired 【 display / non-display 】

  • Pharmacist

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Research project summary 【 display / non-display 】

  • Drug discovery based upon organic synthesis

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Papers 【 display / non-display 】

  • Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain

    Takasaki, I.*; Ogashi, H.; Okada, T.; Shimodaira, A.; Hayakawa, D.; Watanabe, A.; Miyata, A.; Kurihara, T.; Gouda, H.; Toyooka, N.*

    Eur. J. Med. Chem. 2020, 186, 111902.     2020

    Joint Work

  • Synthesis and olfactory evaluation of optically active -alkyl substituted -lactones and whiskey lactone analogues

    Kawasaki, M.*; Kato, D.; Okada, T.; Morita, Y.; Tanaka, Y.; Toyooka, N.

    Tetrahedron 2020, 76, 130984.     2020

    Joint Work

  • Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 human pancreatic cancer cell line

    Tawila, A. M.; Sun, S.; Kim, M. J.; Omar, A. M.; Dibwe, D. F.; Ueda, J.-Y.; Toyooka, N.; Awale, S.*

    Bioorg. Med. Chem. Lett. 2020, 30, 127352.     2020

    Joint Work

  • Fragranol A: A new class of spiro-triflavanoid hybrid with an unprecedented carbon skeleton from Anneslea fragrans

    Omar, A. M.; Sun, S.; Kim, M. J.; Tawila, A. M.; Dibwe, D. F.; Phrutivorapongkul, A.; Toyooka, N.; Awale, S.*

    Tetrahedron Lett. 2020, 61, 152099.     2020

    Joint Work

  • Highly Potent Antiausterity Agents from Callistemon citrinus and Their Mechanism of Action against the PANC-1 Human Pancreatic Cancer Cell Line

    Tawila, A.; Sun, S.; Kim, M. J.; Omar, A.; Dibwe, D.; Ueda, J.; Toyooka, N.; Awale, S.*

    J. Nat. Prod. 2020, 83, 2221-2232.     2020

    Joint Work

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Books 【 display / non-display 】

  • Asymmetric Synthesis of Six-Membered Ring Heterocycles

    Toyooka, N. (Part： Single Work )

    John Wiley & Sons, Ltd.  2009

  • Enantioselective Synthesis of Substituted Pyrrolidine and Piperidines for Natural Product Synthesis

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    Research Signpost  2005

  • Synthetic Studies on Biologically Active Alkaloids Starting from Lactam-Type Chiral Building Blocks

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    Elsevier  2003

  • Synthetic Studies on Dart-Poison Frog Alkaloids

    Toyooka, N.*; Nemoto, H. (Part： Joint Work )

    TRANSWORLD RESEARCH NETWORK  2002

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Review Papers 【 display / non-display 】

  • Synthesis of Poison-frog Alkaloids and Their Pharmacological Effects at Neuronal Nicotinic Acetylcholine Receptors

    Toyooka, N.*; Tsuneki, H.; Kobayashi, S.; Dejun, Z.; Kawasaki, M.; Kimura, I.; Sasaoka, T.; Nemoto, H.

    Current Chemical Biology ( AAA )  1   97 - 114   2007

    Introduction and explanation (scientific journal)   Joint Work

  • Application of Chiral Building Blocks for the Synthesis of Drugs

    Toyooka, N.*; Nemoto, H.

    Drugs Future ( AAA )  27   143 - 158   2002

    Introduction and explanation (scientific journal)   Joint Work

  • Synthetic Studies on Biologically Active Alkaloids

    Toyooka, N.*; Nemoto, H.

    Trends in Heterocyclic Chemistry ( AAA )  8   145 - 154   2002

    Introduction and explanation (scientific journal)   Joint Work

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Industrial Property 【 display / non-display 】

  • Preparation of fused tricyclic compounds as aldose reductase inhibitors

    Industrial Property No WO2009/078423 

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Grant-in-Aid for Scientific Research 【 display / non-display 】

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2015.04  -  2018.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year： 2013.04  -  2016.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2012.04  -  2015.03 

  • Grant-in-Aid for Scientific Research(B)

    Project Year： 2011.04  -  2014.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year： 2010.04  -  2013.03 

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